ABSTRACT Aims To systematically characterize the genetic landscape of dystonia in a Mainland Chinese cohort, where over 60% of patients currently lack a molecular diagnosis due to limited large‐scale genomic studies. Methods Whole‐exome sequencing (WES) was performed in a cohort of 147 clinically diagnosed dystonia pat...
BACKGROUND
Despite a general improvement in the HIV burden over the past two decades, gendered social determinants including intimate partner violence (IPV) continue to affect women's vulnerability to HIV, which could be further exacerbated as resources dwindle over the coming years. Our study aimed to quantify recent...
A. Carter, Meixin Zhang, B. Trejo et al.· The Lancet HIV· 1 citation
Macrophages adapt to hanging tissue environments by rewiring cellular metabolism, and these metabolic programs actively instruct immune functions rather than merely supplying energy. Across health and disease, shifts in glycolysis, mitochondrial oxidative phosphorylation, lipid handling, and amino acid utilization shap...
Jia-Wei He, Bo-Wen Wang, En-Ze Lei et al.· Frontiers in Immunology· 0 citations
The authors' findings provide genetic evidence suggesting a potential association between PFAS exposure and RA risk, and mechanistic studies are warranted to elucidate the biological pathways underlying the potential relationship between PFAS exposure and RA.
