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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Jia-Wen Song

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Open access Sep 2026

Dipyridamole as a Perioperatively Safe Aurora Kinase A Inhibitor for Neoadjuvant Therapy in Esophageal Squamous Cell Carcinoma

Introduction Aurora kinase A (AURKA) is overexpressed in esophageal squamous cell carcinoma (ESCC) and correlates with chemoresistance and poor prognosis. Dedicated AURKA inhibitors show potent target engagement but cause severe myelosuppression incompatible with perioperative esophagectomy. We aimed to identify a comp...

Jia-Wen Song · 0 citations

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