Molecular identification of NF-κB subunit RelA in Manila clam (Ruditapes philippinarum) and its regulatory role in inflammatory response during Vibrio parahaemolyticus infection.
Results demonstrate that RpRelA, as a core NF-κB subunit, positively regulates the inflammatory response during V. parahaemolyticus infection in Manila clam, and provide new insights into the immune regulatory mechanism of bivalves against bacterial infection.