Jia-Xiang Du

Evaluation of primate anti-pig xenoreactive immune responses using immortalized aortic endothelial cells from genetically modified pigs

Porcine vascular endothelial cells are primary targets of humoral and cellular immune responses in pig-to-primate organ xenotransplantation. Although porcine aortic endothelial cells (PAECs) are widely used to evaluate primate anti-pig immune responses, their limited proliferative capacity poses a significant obstacle...