Swine acute diarrhea syndrome coronavirus nsp10 antagonizes IFN-λ1 production via synergizing with hnRNPU and blocking IRF1 NUclear Translocation.
Swine acute diarrhea syndrome coronavirus (SADS-CoV) is a bat-origin porcine enteric alphacoronavirus first identified in Guangdong, China in 2017, which causes severe watery diarrhea and high mortality in neonatal piglets, leading to in substantial economic losses to the global swine industry. Here, we report that SAD...