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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Jia-Xu Wan

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Open access Sep 2026

Mycobacterium tuberculosis Rv0158 negatively regulates the cGAS-STING pathway mediated type I IFN production and enhances intracellular survival.

Overall, the finding identified a new bacterial factor Rv0158, which improves the understanding of the immune evasion mechanisms of M. tb, and suggests that Rv0158 may indirectly facilitate STING degradation or modulate its stability through host-interacting partners.

Zheng-Zhong Xu, Min-Li Geng, Zhi-Hong Yao et al. · 0 citations
Sep 2026

Mycobacterium tuberculosis Rv3248c Inhibits Type I Interferon Response and Promotes Intracellular Survival by Mediating Ubiquitin-Proteasome-Dependent Degradation of TBK1

Findings identify a previously uncharacterized mechanism by which M. tb dampens the IFN-I response by targeting TBK1, highlighting Rv3248c as a contributor to pathogenesis and a potential therapeutic target.

Zheng-Zhong Xu, Min-Li Geng, Zhi-Fang Zhang et al. · 0 citations

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