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Author

Jia-Xuan Li

2 papers indexed here

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Sep 2026

A steric hindrance-regulated autocatalytic CRISPR/Cas12a system for direct and amplification-free microRNA detection.

We constructed a CRISPR/Cas12a autocatalytic system based on a miRNA-triggered overhang blocker (OB) cleavage-recombination framework, in which Cas12a sequentially removed steric hindrance to initiate cyclic autocatalysis, enabling exponential signal amplification for visual miRNA detection without target pre-amplifica...

Wei-Su Kong, Jia-Xuan Li, Ru-Yue Wei et al. · 0 citations
Open access Sep 2026

AuPt bimetallic nanocatalyst-amplified luminol-dissolved oxygen electrochemiluminescence for interferon-γ immunosensing

Interferon-γ (IFN-γ) is a pivotal inflammatory cytokine whose abnormal expression is associated with autoimmune disorders, infectious diseases, and cancer. Herein, a signal-off electrochemiluminescence (ECL) immunosensor was developed by integrating catalytic signal amplification with oriented antibody immobilization....

Huan-Rui Wang, Jia-Xuan Li, Liang-Yi Cui · 3 citations

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