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Author

Jia Yang

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Review Aug 2026

Selective PARP1 inhibitors (2021–2025): patent landscape, structural evolution, and future therapeutic opportunities

Current patents indicate that adenine-pocket engagement, linker optimization, conformational control, and scaffold innovation are central to achieving high PARP1 selectivity and represent important directions for future intellectual property development.

Ji-Long Duan, Yan-Jing Duan, Dong-Ling Gu et al. · 0 citations

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