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Jia-Yi Tong

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Open access Sep 2026

Discovering repurposable drugs for Alzheimer’s disease and related dementias: target trial emulation using decentralised real-world data

Summary Background Alzheimer’s disease and related dementias (ADRD) affect nearly 6.9 million Americans, with the number expected to triple by 2050, while disease-modifying therapies remain unavailable. Drug repurposing, which identifies new indications for already approved medications, offers a more efficient and cost...

Qiong Wu, Lu Li, Yu-Qing Lei et al. · 0 citations
Review Open access Sep 2026

Reproducible study identification and selection in systematic reviews: barriers and paths forward

Abstract Systematic reviews are foundational to evidence-based practice, but the reproducibility and auditability of study identification and selection remain persistent challenges. Existing reporting standards, such as Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 and PRISMA-Search e...

Li-Feng Lin, Xing Xing, Chong Wu et al. · 0 citations

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