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Jia-Ying Lei

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Open access Sep 2026

Cross-Serotype Protection of a PstS-YidR Fusion mRNA Vaccine Against Systemic Infection and Endogenous Endophthalmitis Caused by Hypervirulent Klebsiella pneumoniae

Background: Hypervirulent Klebsiella pneumoniae (K. pneumoniae) easily causes bacteremia and liver abscess, and invades the eye via blood circulation to trigger blinding endogenous endophthalmitis. Widespread multidrug resistance limits antibiotic treatment, while traditional capsular polysaccharide vaccines cannot pro...

Jia-Ying Lei, Xin-Xin Lu, Ti-Yun Han et al. · 0 citations

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