Open access
Aug 2026
Discovery of antimicrobial peptides from incomplete biosynthetic gene clusters to combat multidrug-resistant bacteria
An evolution-inspired approach to reconstruct and predict AMPs from partial BGCs is presented and a promising therapeutic candidate is introduced, NP001, which effectively counteracts polymyxin-resistant pathogens.
Ya‐Li Tang, Xin Cheng, Jing Zhou et al.
· Cell Reports Medicine · 0 citations