Jia-Yu Wang

The Dual Impact of Cocrystal Formers: Contrasting Effects of Diprophylline and Theobromine on the Solid-State Characteristics and In Vivo Pharmacokinetics of Myricetin

Myricetin (MYR), also known chemically as 3,5,7,3′,4′,5′-hexahydroxyflavone, is abundantly present in traditional Chinese medicine, various fruits, and other medicinal substances. It is a natural compound renowned for its extensive pharmacological activities. Nevertheless, its extremely low water solubility poses a s...

BRCAness-Driven Prognostic Model and Regimen-Specific Therapeutic Implications in Triple-Negative Breast Cancer With Residual Disease After Neoadjuvant Chemotherapy.

Adjuvant T-DM1 versus trastuzumab plus pertuzumab for residual disease after neoadjuvant dual HER2 blockade in HER2-positive early breast cancer: a multicenter real-world study

Despite the established benefit of adjuvant trastuzumab emtansine (T-DM1) over trastuzumab in HER2-positive early breast cancer (eBC) with residual disease after neoadjuvant chemotherapy plus HER2-targeted therapy, comparison of efficacy between T-DM1 and dual HER2 blockade (trastuzumab plus pertuzumab, HP) remai...

A predictive model of survival in early-stage medullary breast carcinoma: a population-based study.

A clinical model incorporating age (≥65 years), T stage (T3/T4), N stage (N2/N3), and chemotherapy (no) was developed to predict inferior OS in early-stage MedBC.