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Author

Jia Zhu

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Sep 2026

Targeting PCK2 alleviates GERD by suppressing MAPK-dependent endoplasmic reticulum stress and oxidative stress-induced apoptosis.

Gastroesophageal reflux disease (GERD) is a digestive disease characterized by endoplasmic reticulum stress (ERS) imbalance and oxidative stress-induced cellular injury. However, the key ERS-related regulators involved in GERD progression remain unclear. Here, we identified PCK2 as a novel GERD-associated ERS regulator...

Na Wang, Jia Zhu · 0 citations
Open access Sep 2026

Targetable Preventive Metabolites: Revealing the Pathways from Air Pollution Mixtures to Hypertension Through Integrated Exposure-Metabolomics

C6-carnitine and other preventable metabolites are important biological mediators of air pollution mixture-induced hypertension, partially illuminating the molecular link between environmental exposure and cardiovascular metabolic disorders.

Jia Zhu · 0 citations

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