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Author

Jiajie Xia

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Open access Sep 2026

ZBP1‐mediated Treg cell dysfunction exacerbates neuroimmune dysregulation in Alzheimer's disease under metabolic stress

Abstract INTRODUCTION Metabolic stress increases Alzheimer's disease (AD) risk, but mechanisms linking metabolic dysfunction to neuroimmune dysregulation remain unclear. METHODS We assessed cognition in community‐dwelling participants and used high‐fat diet (HFD)‐fed 5xFAD mice, high glucose and high palmitate (HGHP)‐t...

Shan-Shan Huang, Zeng-Yu Zhang, Jia-Jie Xia et al. · 0 citations
Review Open access Aug 2026

Regulatory T cells in intracerebral hemorrhage: mechanisms of immunomodulation and therapeutic potential

It is proposed that Treg-centered immunomodulation represents a promising but still underdeveloped therapeutic strategy for improving recovery after ICH and particular attention to emerging approaches such as antigen-specific CAR-Treg cells and gut–brain axis modulation.

Jia-Jie Xia, Xinjie Gao, Shanshan Huang · 0 citations

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