Author

Jian Dong

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Open access Oct 2026

An Injectable and Self‐Reinforced Piezoelectric Hydrogel for Irregular Bone Defects Regeneration: Dynamic Epigenetic Regulation Approach

ABSTRACT Irregular bone defects demand biomaterials that can be delivered into complex shapes while offering gradually developing mechanical strength and bioactive electrical stimulation‐two critical properties rarely obtained simultaneously. Here, we develop an injectable, polymer‐induced self‐reinforcing and piezoele...

Yu-Kai Huang, Juan Li, Miao-Miao Yang et al. · Advancement of science · 0 citations

Sep 2026

Nanocatalytic Phase Separation Augments Tumor‐specific cGAS‐STING Activation for Spinal Metastasized Breast Cancer Metalloimmunotherapy

The cGAS‐STING pathway is a pivotal therapeutic target for antitumor immunity, yet clinical translation of its small‐molecule agonists is hindered by poor tumor specificity, suboptimal pharmacokinetics, and systemic off‐target effects. Here, we report a nanocatalytic strategy based on a tumor microenvironment (TME)‐res...

Hao Qin, Jia-Qian Wang, Jian Zhou et al. · Advanced Healthcare Material... · 0 citations

Open access Jul 2026

Highly penetrative nanocarrier modulates tumor bacteria to enhance oxygen-free photo immunotherapy in spinal metastatic cancer.

A novel charge-enrichment and light-activated biomimetic nanosystem, designated as polyion liquid-bridged eosin Y (PIL-BEY), which offers a promising strategy for treating invasive metastatic tumors.

Chao Jia, Hongwei Lu, Jin-Jin Wang et al. · Journal of Nanobiotechnology · 0 citations