Author

Jian-Fen Su

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Open access Aug 2026

Pharmacokinetic and bioequivalence study of enteric-coated omeprazole capsule in healthy Chinese subjects under fasting and fed conditions

This study aimed to evaluate the bioequivalence of a generic enteric-coated omeprazole capsule compared with the reference product (Losec®) in healthy Chinese subjects. The fasting study was conducted using a randomized, single-centre, single-dose, two-period, two-sequence crossover design. The fed study was a randomiz...

Fucai Zhang, Jingyi Xie, Yong Li et al. · BMC Pharmacology and Toxicol... · 0 citations

Open access Sep 2026

Pharmacokinetic and bioequivalence evaluation of teneligliptin hydrobromide tablets following single-dose administration in healthy Chinese volunteers under fasting and fed conditions

By inhibiting dipeptidyl peptidase-4 (DPP-4), teneligliptin provides a therapeutic option for type 2 diabetes mellitus (T2DM) that is widely used in Asia. A generic product could lessen treatment costs, provided that its systemic availability is equivalent to that of the branded formulation. Such comparative informatio...

Zhao-Feng Guan, Ming-Qi Chen, Bi-Ying Wei et al. · BMC Pharmacology and Toxicol... · 0 citations