Network toxicology, transcriptomics, immune infiltration, and machine learning-based construction of an environmental endocrine disruptor exposure-associated predictive model for osteonecrosis of the femoral head.
To investigate the potential molecular links between nonylphenol (NP) exposure and osteonecrosis of the femoral head (ONFH), we employed an integrated strategy combining network toxicology, transcriptomic analysis, weighted gene co-expression network analysis (WGCNA), machine learning, immune infiltration analysis, mol...