Open access
Oct 2026
Targeting macrophage-derived oncostatin M preserves cardiomyocyte mitochondrial bioenergetics and contractile function in fulminant myocarditis.
BACKGROUND Fulminant myocarditis (FM) is an acute inflammatory cardiomyopathy with high risk of cardiogenic shock. Current management relies largely on circulatory support, while mechanism-based pharmacological targets remain poorly defined. METHODS Cardiac CD45+ single-cell RNA sequencing, whole-heart single-nucleus...
Yong-Cui Yan, Ze-Yu Sun, Yi He et al.
· Pharmacological Research · 0 citations