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Jian-Guang Xu

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Open access Aug 2026

Bridging structure and function: triple network remodeling driven by white matter hyperintensities in vascular cognitive impairment.

Cerebral small vessel disease-induced vascular cognitive impairment (VCI) is a major contributor to the pathogenesis of dementia. Accumulating evidence suggests that VCI disrupts large-scale brain networks, but how it selectively impairs inter-network connectivity and contributes to specific cognitive deficits remains...

Jing Jin, Jie Ma, Jia-Jia Wu et al. · 0 citations
Sep 2026

APOE-centered transcriptional convergence underlying diverse dementia subtypes.

BackgroundDementia subtypes exhibit diverse clinical and pathological features, yet may share convergent molecular underpinnings. Identifying these common pathways is critical for unified therapeutic strategies.ObjectiveTo delineate the shared genetic architecture and convergent molecular pathways underlying diverse de...

Zhi-Jie Xu, Jie Ma, G. M. Giuffré et al. · 0 citations
Open access Aug 2026

Altered resting-state network effects in patients after stroke following cortico-cortical target transcranial magnetic stimulation

It is suggested that ccPAS can facilitate recovery by modulating higher-order, distributed brain networks in chronic stroke patients by inducing widespread reorganization of RSNs, enhancing connectivity within and between networks subserving attention, visuospatial processing and sensorimotor integration.

Xiang-Xin Xing, Jia-Jia Wu, Jie Ma et al. · 0 citations
Clinical trial Open access Sep 2026

Clinical efficacy and cortical network modulation of a multimodal sensory feedback upper-limb rehabilitation robot for post-stroke upper-limb recovery: a randomized controlled trial

Adding multimodal sensory-feedback robot-assisted training to dose-matched conventional rehabilitation to improve short-term post-stroke upper-limb motor recovery may improve short-term rehabilitation outcomes.

Li-Hui Zhao, Jun-Peng Zhang, Jia-Jia Wu et al. · 0 citations
Open access Aug 2026

Early functional disconnection of the basal forebrain-hippocampal system predicts memory impairment in amnestic mild cognitive impairment.

Directional connectivity alterations within the BF-hippocampal-cortical axis were observed in patients with aMCI in the absence of detectable macroscopic atrophy, highlighting the potential contribution of BF-related network dysfunction to early disease processes.

Juan-Juan Lu, Zhi-Jie Xu, Jie Ma et al. · 0 citations

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