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Author

Jian-Guo Zhu

2 papers indexed here

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Sep 2026

MCM10 Modulates Lipid Metabolic Reprogramming via the USP7-FASN Axis to Accelerate Renal Cell Carcinoma Progression.

Metabolic reprogramming, particularly dysregulated lipid metabolism, is a hallmark of clear cell renal cell carcinoma (ccRCC) progression. However, the upstream regulators responsible for lipid metabolic rewiring remain largely unknown. Here, we integrated single-cell RNA sequencing, spatial transcriptomics, and functi...

Ashuai Du, Ke-Hua Jiang, Kai Li et al. · 0 citations
Open access Sep 2026

Multimodal integration of pathomics and single-cell transcriptomics reveals CDC20 as a link between prostate cancer recurrence and benzo[a]pyrene-responsive phenotypes

Introduction Prostate cancer recurrence reflects molecular and histological heterogeneity, yet the cellular states harboring recurrence-associated signals and their potential environmental modifiers remain incompletely understood. Methods We integrated single-cell RNA sequencing, bulk transcriptomes with recurrence ann...

Xu-Chao Dai, Wei Gu, Bo Yu et al. · 0 citations

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