Author

Jian-Hua Sui

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Open access Sep 2026

Identification of Galectin-9 (Gal-9) as a B7-H4 binding partner and characterization of their glycosylation-dependent interaction that modulates T cell signaling within a multi-ligand/receptor network

B7-H4, a member of the B7 family, is broadly expressed on various cancer cells and has been implicated in negative immune regulation, particularly in suppressing anti-tumor immunity. However, its receptor and the mechanisms underlying its immunosuppression remain poorly understood. Here, we identify Galectin-9 (Gal-9)...

Ravear Zhiqiang Wang, Fang Yang, Jian-Hua Sui · PLoS ONE · 0 citations

Open access Aug 2026

An IgG-like fusion protein comprising an anti-Spike S2 antibody and ACE2 exhibits potent and broad neutralization against SARS-CoV-2 and variants of concern

A bispecific fusion protein with potent broad-spectrum neutralizing activity against SARS-CoV-2 variants is developed and provides a promising strategy for next-generation coronavirus biologics.

Zhi-Zhong Wei, Ximing Liu, Kailun Wang et al. · Antibody Therapeutics · 0 citations