Diosmetin as a Promising Anticancer Agent: Mechanisms, Structural Optimization, and Advanced Delivery Systems
Diosmetin (Dio) is a natural flavonoid with broad-spectrum anticancer activity against various malignancies through mechanisms involving cell cycle arrest, apoptosis induction, metastasis inhibition, and modulation of oncogenic signaling pathways such as STAT3/c-Myc and PI3K/AKT/mTOR; with the exception of CDK2, whic...