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Jian-Li Han

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Review Open access Sep 2026

Astragaloside IV in hepatocellular carcinoma: repolarizing macrophages to reprogram the tumor microenvironment

The establishment of an immunosuppressive tumor microenvironment (TME) represents a central mechanism underlying the failure of conventional therapies and resistance to immunotherapy in hepatocellular carcinoma (HCC). Tumor-associated macrophages (TAMs), as the most abundant immune cell population within this microenvi...

Peng Ma, Xin-Da Lu, Jian-Li Han et al. · 0 citations

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