CRISPR Nanomachinery-Sensitized Nanocatalytic Tumor Ferroptosis in Triple-Negative Breast Cancer.
The luminal androgen receptor (LAR) subtype of triple-negative breast cancer (TNBC) represents a formidable therapeutic challenge, necessitating sophisticated strategies that exploit unique tumor vulnerabilities. In the present work, we introduce a biomimetic nanotherapeutic that integrates single-atom iron nanocatalys...