Jian-Mei Song

A central hub for convergence: multi-layer genomic networks reveal lineage-specific plasmid compatibility driving hypervirulence and carbapenem resistance in ST11 Klebsiella pneumoniae

The convergence of hypervirulence and carbapenem resistance in Klebsiella pneumoniae represents a critical threat to global public health. However, the genomic mechanisms underlying this convergence, particularly the interplay between chromosomal background and mobile genetic elements, remain incompletely understoo...