Sep 2026
Panaxytriol up-regulates CYP2B6 expression through PXR and CAR and their interactions with RXRα and SRC-1.
ETHNOPHARMACOLOGICAL RELEVANCE Cytochrome P450 2B6 (CYP2B6) is a critical drug-metabolizing enzyme, and its expression is regulated by the nuclear receptors. Panaxytriol (PXT), a prominent bioactive constituent extracted from the roots of Panax ginseng C.A. Meyer, was found to induce cytochrome P450 3A4 (CYP3A4) via pr...
Lin Huang, Yin-Yue Du, Qi Gu et al.
· Journal of Ethnopharmacology · 0 citations