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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jian-Ping Ding

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Aug 2026

Cryo-EM structure of the WDR11-FAM91A1-C17orf75 complex involved in retrograde trafficking.

Retrograde trafficking from endosomes to trans-Golgi network is essential for cellular homeostasis. While the WDR11-FAM91A1-C17orf75 (WFC) complex facilitates this process, its structural organization and the role of C17orf75 remain unclear. Here, we present cryo-EM structures of human WFC complex in monomeric and dime...

Yifan Zhang, Zhi-Min Liu, Zi-Rong Chen et al. · 0 citations
Open access Aug 2026

Structure and enzymatic properties of human retroviral-like aspartic protease 1 and functional roles of disease-associated mutations.

Structural analysis reveals that ASPRV1-14 possesses distinctly hydrophobic S2/S2' pockets, dictating a strict requirement for hydrophobic residues at the P2/P2' positions of substrates and explaining its resistance to most HIV-1 PR inhibitors, except indinavir.

Xueqian Feng, Zi-Lian Chen, Chao Lan et al. · 0 citations

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