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Author

Jian-Ping Liu

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Open access Aug 2026

Integrative analysis of gut microbiota, plasma metabolome, and gene expression identifies causal mediators in Graves’ disease pathogenesis

The composition of gut microbiota and its related metabolites promote the development of GD through the modulation of gene expression in peripheral blood mononuclear cells through the modulation of gene expression in peripheral blood mononuclear cells.

Yuying Zhang, Jin’e Li, Yunfei Luo et al. · 0 citations
Jul 2026

METTL3‐Activated IDO1‐Kynurenine Pathway in Insulin‐Producing Cells Enhances Graft Survival and Attenuates Endogenous Islet Apoptosis in Diabetic Mice

It is shown that METTL3 overexpression is associated with IDO1 upregulation and elevated systemic Kyn levels, which suggest that the METTL3‐IDO1‐Kyn pathway may be a potential target for improving cell replacement therapy for diabetes.

Shan Xu, Li-Xuan Fang, Jia-Jun Qiu et al. · 0 citations

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