Open access
Sep 2026
Ginsenoside Rg5 mitigates adenine-induced renal fibrosis by regulating the SIRT7/NETs/NLRP3 pyroptosis axis.
This study examined the protective effects of Rg5 against renal fibrosis and elucidated its underlying immunomodulatory mechanisms. A mouse model of renal fibrosis was generated through adenine administration, and Rg5 was administered orally to assess its preventative effects. Renal tubular epithelial cells (RTECs, HK-...
Jiang-Tao Zhong, Zi-Yi Xu, Ze-Long Wang et al.
· International Immunopharmaco... · 0 citations