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Jian-Tao Liu

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Open access Sep 2026

HMOX2-driven crosstalk between vascular aging and heart failure: A multimodal bioinformatics and explainable machine learning approach with experimental validation

Purpose The molecular mechanisms linking vascular aging (VA) and heart failure (HF) remain elusive, hindering therapeutic strategies for their comorbidity. This study aimed to identify key biomarkers and pathways potentially involved in VA-HF synergy using integrative computational approaches. Methods We analyzed the G...

Jin-Ze Li, Gui-Ting Zhou, Qiao-Chu Wang et al. · 0 citations

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