Baicalein-loaded rhamnolipid nanomicelles target mitochondrial dysfunction and activate the cGAS-STING pathway for triple-negative breast cancer therapy.
Triple-negative breast cancer (TNBC) remains an intractable malignancy due to the lack of specific therapeutic targets and high metastatic potential. Herein, we fabricated rhamnolipid (RL)-encapsulated baicalein (BAI) nanomicelles (RL/BAI) via a thin-film hydration method. Molecular dynamics (MD) simulations revealed t...