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Jian-Xiang Huang

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Sep 2026

Combined low-dose (2R,6R)-Hydroxynorketamine and memantine restore BDNF/TrkB signaling and synaptic function in an LPS-induced model of depressive-like behavior in male mice.

It is suggested that MEM and low-dose HNK counteract inflammation-associated neural dysfunction in association with Trk-related signaling and require validation in both sexes before translational advantages can be inferred.

Xiao-Li Jia, Qi-Chao Gong, Bo-Cheng Xiong et al. · 0 citations

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