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Author

Jianxin Liu

2 papers indexed here

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Open access Dec 2026

Disporum cantoniense suppresses non‑small cell lung cancer through AMPK/mTOR/ULK1‑mediated autophagy‑dependent apoptosis.

Non‑small cell lung cancer (NSCLC) remains a leading cause of cancer‑associated mortality and urgently requires new therapeutic agents. In the present study, phenotypic screening of natural herbal extracts was performed, identifying Disporum cantoniense extract as a selective inhibitor of NSCLC cell viability. Bioactiv...

Chi Feng, Yu-Jiao Ji, Ren-Qiang Chen et al. · 0 citations
Open access Jul 2026

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Consistently, 2DG or liproxstatin-1 reduced ferroptosis-associated oxidative damage and improved behavioral or cognitive deficits in transgenic C. elegans, supporting a substantial contribution of AMPK-ACC1-associated signaling to ferroptosis suppression under energy stress.

Yuanyuan Yong, Yu-Xin Hu, Qian Feng et al. · 0 citations

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