OBJECTIVES
Proliferative lupus nephritis (PLN) is associated with poorer renal outcomes than non-proliferative lupus nephritis. Although kidney biopsy remains the gold standard for histologic classification, its use may be limited by invasiveness, contraindications, and limited healthcare access. We aimed to develop an...
Zi-Shan Lin, Wen-Feng Wang, Xin-Tian Li et al.· Rheumatology· 0 citations
Background Tertiary lymphoid structures (TLS) are organized immune aggregates that develop in non-lymphoid tissues during chronic inflammation and are associated with adverse outcomes in various kidney diseases. Their role in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis remains poorly charac...
Yu-Jia Wang, Kai-Qi Huang, Jia-Ye Fang et al.· Frontiers in Immunology· 0 citations
Abstract Introduction Selective glomerular hypofiltration syndrome (SGHS), defined by a low ratio of estimated glomerular filtration rate using cystatin C (eGFRcys) to estimated glomerular filtration rate using creatinine (eGFRcr), has emerged as a novel kidney dysfunction phenotype. Its role in diabetic kidney disease...
Yuan Fang, Xiao-Dan Guo, Liu-Ting Zhong et al.· BMJ Open Diabetes Research &...· 0 citations
VCAN and ESM1 are promising biomarkers reflecting distinct, cell-type-enriched patterns of NET-related glomerular injury in DKD, supporting a dual-track model of endothelial dysfunction and paracrine matrix remodeling.
