Sep 2026
Targeted quantification of 25 tryptophan metabolites across three metabolic pathways in serum by ultra-high-performance liquid chromatography coupled with quadrupole orbitrap high-resolution mass spectrometry.
Tryptophan metabolism encompasses three interconnected pathways, namely the kynurenine, serotonin, and gut microbiota-mediated indole pathways, which contribute to immune regulation, neural signalling, and host-microbiota interactions. Quantitative analysis of metabolites spanning these pathways remains challenging bec...
Min Guo, Zhi-Hua Zhang, Li-Ping Cao et al.
· Journal of Pharmaceutical an... · 0 citations