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Jian-Ye Yuan

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Open access Sep 2026

Succinylation-related gene GLS regulates mannose and glycerophospholipid metabolism to promote irritable bowel syndrome: an integrated study combining Mendelian randomization, SMR, and mediation analysis

To investigate whether succinylation-related genes participate in irritable bowel syndrome (IBS) pathogenesis by regulating blood metabolites. Genome-wide association study (GWAS) data for cis-expression Quantitative Trait Loci (cis-eQTLs) were obtained from eQTLGen Consortium. Blood metabolite GWAS data were derived f...

Lian Mo, Yan Zhou, Yue Wu et al. · 0 citations

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