Chronic Exposure to Benzo[a]pyrene and Catechol Drives Lung Cancer Invasion via Convergent Extracellular Matrix Remodeling and Metabolic Reprogramming.
Chronic low-level exposure to environmentally relevant pollutants is a widespread yet underappreciated risk factor in cancer progression. This study aimed to determine whether prolonged exposure to benzo[a]pyrene (B[a]P) and catechol (CL) enhanced malignant phenotypes in human lung cancer A549 cells. Following 3 months...