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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Jian Zhang

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Open access Aug 2026

A knowledge-driven framework for predicting single-cell responses for unprofiled drugs

An artificial intelligence framework that integrates biological mechanism knowledge to predict how cells respond to chemical perturbation, improving generalization to untested drugs and prioritizing cancer drug candidates in virtual screening is introduced.

Jinghao Feng, Zi-Heng Zhao, Xiaoman Zhang et al. · 2 citations
Open access Aug 2026

Discovery of Aurora A/HDAC dual-target inhibitors: broad-spectrum in vitro antitumor activity and in vivo pharmacokinetic limitations.

Z20 is a potent Aurora A/HDAC dual-target inhibitor in vitro, while its pharmacokinetic defects limit clinical potential, which highlights the necessity of optimizing pharmacokinetic profiles for translating in vitro potency to in vivo efficacy.

Li-Rong Zhang, Xuewen Zhang, Jie Zhong et al. · 0 citations

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