Review
Open access
Aug 2026
The NRF2 signaling pathway in hepatocellular carcinoma: dual roles, epigenetic reprogramming, and therapeutic opportunities in metabolic vulnerability
NRF2-related metabolic pathways and redox defense systems exhibit potential metabolically targetable vulnerabilities, providing a theoretical basis for combined induction of ferrocytosis and metabolic intervention in HCC.
Yue Wang, Lingwei Gao, Hao-Bo Yang et al.
· Frontiers in Oncology · 0 citations