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Jian-Zhong Liu

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Oct 2026

A hierarchical systems metabolic engineering framework for modular construction of Mycolicibacterium neoaurumcell factories for efficient phytosterol bioconversion.

Androst-4-ene-3,17-dione (AD), Androst-1,4-diene-3,17-dione (ADD), and 9-hydroxy-4-androstene-3,17-dione (9-OHAD) are valuable C19 steroid intermediates derived from low-cost phytosterol bioconversionby Mycolicibacterium neoaurum. However, its slow growth rate, limited sterol uptake and complex metabolic networks restr...

Jun-Feng Li, Mei-Ling Xiao, Gui-Zhen Liu et al. · 0 citations

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