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Jiang-Li Han

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Open access Sep 2026

The mechanism of NEDD4 attenuating intracerebral hemorrhage injury through restoring glymphatic function by ubiquitin-mediated degradation of LPAR1.

BACKGROUND Intracerebral hemorrhage (ICH) induces severe neurological injury, and the glymphatic system plays a critical role in post-ICH brain recovery. This study investigated the role of neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4), an E3 ubiquitin ligase, in modulating glymphatic...

Cong Tan, Xiao-Bing Zheng, Li Peng et al. · 0 citations

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