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Author

Jiang-Qing Dong

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Sep 2026

Pocket-Oriented Design of Benzene-Fused Pyridinecarboxylates as Potent Synthetic Auxin Herbicides

Synthetic auxin herbicides (SAHs) with pyridinecarboxylate scaffolds are valued for their high efficacy and favorable safety, yet their limited structural diversity has constrained further development. In this study, we analyzed sequence variations in TIR1/AFBs among different species and employed a pocket-oriented m...

Wen-Yi Yang, Zi-Xiang Meng, Xiao-Ting Wang et al. · 0 citations
Review Open access Sep 2026

The HCMV terminase as an antiviral target: structural insights, inhibitory mechanisms, and the era of letermovir

Current understanding of the interaction between letermovir and the HCMV terminase is summarized, focusing on structural organization, inhibitory mechanisms, resistance mutations, and emerging approaches for next-generation inhibitor development, and highlighting key unresolved questions that will guide future structur...

Guo-Jun Chen, Yu-Qi Li, Jin-Rui Chen et al. · 0 citations
Open access Aug 2026

Molecular basis of Arabidopsis ABCC2 in plant detoxification

Cryo-electron microscopy structures of At ABCC2 provide new insights into the detoxi cation mechanism of At ABCC2 and highlight the potential for using ABCC transporters to develop herbicide-resistant crops.

Jiang-Qing Dong, Tai-Li Yang, Xin-He Yu et al. · 0 citations

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