Gut Microbiota-Associated Suppression of Intestinal β-Catenin Signaling Contributes to Barrier Dysfunction and Hepatic Pyroptosis Following SCCPs Exposure.
Short-chain chlorinated paraffins (SCCPs), as persistent organic pollutants, pose potential health threats, yet their toxicological mechanisms remain incompletely elucidated. This study demonstrates that exposure to SCCPs can induce liver injury in mice. Specifically, SCCPs interfere with the expression of intestinal t...