Author

Jiang-Bo Li

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Review Open access Sep 2026

Depression and shortened survival in patients with cancer: a neuroimmune framework for bidirectional pathogenesis and therapeutic interception

Although depression is highly prevalent among patients with cancer and is consistently linked to shortened survival, its underlying biological mechanisms remain incompletely understood. While emerging evidence suggests that depression reshapes both systemic and tumor-localized immunity via β-adrenergic and glucocortico...

Jiang-Bo Li, Wei Rong, Bin-Hui Xiao et al. · Frontiers in Immunology · 0 citations

Aug 2026

Altered expression of NUCB2/nesfatin-1 in plasma, hypothalamus and brainstem is associated with HPA axis activity and TPH expression in chronically stressed rats.

Preliminary correlational evidence for coordinated NUCB2/nesfatin-1 changes across peripheral and central systems under stress-induced depression is provided, suggesting NUCB2/nesfatin-1 may link neuroendocrine activity and serotonergic plasticity with the brainstem as a core site.

Shengjuan Wu, Gaohua Wang, Jiangbo Li · Pharmacology, Biochemistry a... · 0 citations