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Jianhua Liao

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Open access Sep 2026

Time-Resolved Proteomic and Phenotypic Analysis of the MRSA Response to (+)-Usnic Acid

To characterize the antibacterial response of methicillin-resistant Staphylococcus aureus (MRSA) to (+)-usnic acid using time-resolved proteomics and phenotypic assays. MRSA cultures were exposed to (+)-usnic acid at the minimum inhibitory concentration (MIC; 8 mg/L) and sampled at 30, 60, and 120 min....

Jian-Hua Liao, Jun Cheng, Yu-Zhi Shao et al. · 0 citations
Open access Aug 2026

Disruption of ytrE attenuates methicillin-resistant Staphylococcus aureus virulence and compromises membrane integrity and oxidative stress resistance

It is suggested that ytrE contributes to MRSA pathogenic fitness by supporting envelope homeostasis and resistance to oxidative stress and non-essential factors involved in membrane stability may represent potential targets for future anti-virulence studies.

Jianhua Liao, Chaodan Shao, Dongli Yu et al. · 0 citations

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