ETHNOPHARMACOLOGICAL RELEVANCE
Psoralea Fructus (PF), the dried ripe fruit of Psoralea corylifolia L., is a widely utilized Chinese medicinal herb with a long-established history in clinical practice and is known for its diverse biological activities. Although furanocoumarin is potentially hepatotoxic, exposure levels...
Shan Han, Zhen-Dong Wang, Li-Wen Zhang et al.· Journal of Ethnopharmacology· 0 citations
The structure-based covalent modifications that generate new nonpeptidic covalent Mpro inhibitors are described that may support the deuterated compound as a new lead for developing anti-SARS-CoV-2 drugs and further reveal the feasibility of using chloroacetyl for structure-based covalent drug design.
Honglei Bao, Ling-Chen Sun, Shi-Lin Gong et al.· ACS Bio & Med Chem Au· 0 citations
In this work, red-fluorescent silver nanoclusters (MMTA@Ag NCs) with aggregation-induced emission (AIE) properties were synthesized via a facile one-pot strategy at room temperature using 2-mercapto-4-methyl-5-thiazoleacetic acid (MMTA) as the capping ligand. The as-prepared Ag NCs initially exhibited weak fluorescence...
By moving beyond generic strategies for BBB penetration to address the distinctive pharmacotherapeutic shortcomings of depression, engineered nanomedicine holds great promise for advancing next-generation antidepressant therapies that achieve rapid onset, precise intervention, and comprehensive improvement in patient q...
Mijia Zhang, En-Yao He, Y. Xiong et al.· Advanced Healthcare Material...· 0 citations
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