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Author

Jianlin Xu

2 papers indexed here

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Sep 2026

Echinococcus granulosus antigen 5: a novel immunomodulator that targets NF-κB signaling to suppress inflammation in THP-1 monocyte.

Chronic infection by Echinococcus granulosus leads to the establishment of fluid-filled cysts (hydatid cysts) in the liver or lungs of infected hosts, which can escape destruction by the host immune system for long periods. Ag5 is abundantly expressed in the cyst fluid of the fine-grained E. granulosus and plays an imp...

Fan Zhang, Zhi Li, Jian-Lin Xu et al. · 0 citations
Open access Jul 2026

RNF220 safeguards meiotic synapsis and male fertility by antagonizing SYCE1 ubiquitination

A homozygous mutation in RNF220 , encoding a RING-type E3 ubiquitin ligase, is associated with male infertility featuring small-headed sperm, but the precise roles and mechanisms of RNF220 in spermatogenesis remain elusive. Here, we explored the function of RNF220 in spermatogenesis using a Stra8-Cre-mediated...

Jing-Mei Cha, Huijuan Lin, Yingqian Xia et al. · 0 citations

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