Open access
Aug 2026
Prognostic signatures associated with immune and macrophage phenotypes in colorectal cancer: integrated single-cell and bulk transcriptomic analyses
Colorectal cancer (CRC) progression is closely associated with chronic inflammation and immune suppression mediated by M2 macrophages. This study systematically analyzed immune-related and macrophage polarization–related genes in CRC by integrating The Cancer Genome Atlas CRC dataset to identify differentially expr...
Yuan Yuan, Bing-Xi Zhou, Jin Liu et al.
· Scientific Reports · 0 citations