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This study aims to systematically assess the global burden of musculoskeletal (MSK) diseases caused by high body mass index (BMI) and to analyze its temporal trends and cross-national inequalities. Data were extracted from the Global Burden of Disease 2021. We quantified the temporal trends by calculating the estimated...
Osteosarcoma is an aggressive bone malignancy characterized by early metastasis, chemoresistance, and poor prognosis, particularly in recurrent or metastatic cases. The long non-coding RNA PVT1 has been implicated as an oncogene in various cancers, but its therapeutic potential in osteosarcoma remains underexplored. Th...
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