The classical “vascular occlusion” model does not fully account for osteonecrosis of the femoral head (ONFH). Femoral head collapse may progress despite restored perfusion, and ischemia alone cannot adequately explain steroid-associated ONFH. We propose that ONFH involves disruption of bone-vascular-immune homeostasis,...
Yan Wang, Lu-Lu Zhang, Xue-Zhi Liu et al.· Journal of Orthopaedic Trans...· 0 citations
Skeletal muscle plays a central role in whole-body energy homeostasis, metabolic flexibility, and insulin sensitivity, acting as a key integrator of nutritional, mechanical, and pharmacological signals. Although diet, exercise, and pharmacotherapy are often investigated as separate interventions, they converge on share...
Yan Wang, Meng-Ran Qin, Xue-Zhi Liu et al.· Frontiers in Physiology· 0 citations
Bone scaffolds represent a common surgical approach for repairing bone defects, and the clinical demand for effective graft substitutes remains high due to the limited availability of autologous bone. Titanium (Ti) and its alloys are widely used as load‐bearing implants; however, their inherent biological inertness hin...
Jia-Jun Liu, Yan Wang, Xin Li et al.· Macromolecular Bioscience· 0 citations
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